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Kawasaki disease 3

Course: Pathology

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Kawasaki Disease
Kawasaki disease , also known as Mucocutaneous lymph node syndrome and Kawasaki
syndrome, and is defined as an acute febrile illness of early childhood which causes swelling
(inflammation) in children in the walls of small to medium-sized blood vessels that carry blood
throughout the body.
Kawasaki disease commonly leads to inflammation of the coronary arteries, which supply
oxygen-rich blood to the heart.
Kawasaki disease was previously called mucocutaneous lymph node syndrome because it also
causes swelling in glands (lymph nodes) and mucous membranes inside the mouth, nose, eyes
and throat.
Children with Kawasaki disease might have high fever, swollen hands and feet with skin peeling,
and red eyes and tongue. But Kawasaki disease is usually treatable, and most children recover
without serious problems if they receive treatment within 10 days of onset.
Symptoms:-
To receive a diagnosis of Kawasaki disease, a child usually will have a fever greater than 102.2 F
(39 C) for five or more days and at least four of the following signs and symptoms.
An enlarged lymph node in the neck
A rash on the main part of the body or in the genital area
Extremely red eyes without a thick discharge
Swollen, red skin on the palms of the hands and the soles of the feet, with later
peeling of skin on fingers and toes
Red, dry, cracked lips and an extremely red, swollen tongue
The symptoms might not occur at the same time.
Other signs and symptoms that might develop include:
Diarrhoea