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Integumentary system
Human Biomedical Anatomy (BIOM3002)
University of Queensland
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Gross composition of skin varies across the surface of the body. Skin can be thin, hairy, hirsute, the thick skin found over the palms, soles of the feet and flexor surfaces of that is free from the body, skin is composed the epidermis, dermis and hypodermis. We examine these layers in more OpenStax College via Wikimedia 1 The skin is comprised of three main epidermis, dermis and epidermis is the most superficial layer of the skin, and is largely formed terminal maturation. This involves increased keratin production toward the external surface, a process are also that inhabit the responsible for melanin production and pigment individuals with darker skin have increased melanin production, not an of dendritic sensory of the epidermis can be divided into layers (strata) of keratinocytes this reflects their change in properties as they migrate towards the surface. From deepest to most superficial, these layers mitosis of keratinocytes occurs in this keratinocytes are joined tight intercellular junctions called cells secrete lipids and other waterproofing molecules in this cells lose nuclei and drastically increase keratin cells lose all organelles, continue to produce keratinocyte typically takes between 30 40 days to travel from the stratum basale to the OpenStax College via Wikimedia Follicles and Sebaceous hair follicles and sebaceous glands combine to form which is only found glands release their glandular secretions via a holocrine mechanism into the hair The hair follicle itself is associated with which contracts to cause to stand are two main types of sweat the major sweat glands of the human body. a clear, comprised mostly of sodium chloride and water which is involved larger sweat glands, located in the axillary and genital products can be broken down cutaneous microbes, producing body BruceBlaus via Wikimedia 3 The dermis is divided into the papillary and reticular or subcutaneous tissue, is immediately deep to the is a major body store of adipose tissue, and as such can vary in size between individuals depending amount of fatty tissue Relevance Disorders of alopecia is marked autoimmune destruction of hair follicles, causing Like alopecia, vitiligo is an autoimmune disease, where melanocytes are targeted Areas of symmetrical depigmentation appear, which are more apparent in darkerskinned In psoriasis, the mitosis of keratinocytes in the stratum basale is drastically a thickened stratum spinosum. This is clinically apparent as skin, typically knees and
Integumentary system
Course: Human Biomedical Anatomy (BIOM3002)
University: University of Queensland
